CatalogNo.Size

50183P-22ug

50183P-1010ug

50183P-5050ug

50183P-100100ug

50183P-10001000ug

CCL28,alsoknownasMucosae-associatedEpithelialChemokine(MEC),issecretedbygastrointestinalandnon-intestinalmucosalcells.ItregulateschemotaxisofcellsexpressingsurfacereceptorsCCR3andCCR10.Thischemokineisconstitutivelyexpressedinthecolon,butitslevelscanbeincreasedbypro-inflammatorycytokinesandcertainbacterialproductsimplyingaroleineffectorcellrecruitmenttositesofepithelialinjury.CCL28hasalsobeenimplicatedinthemigrationofIgA-expressingcellstothemammarygland,salivarygland,intestineandothermucosaltissues.Ithasalsobeenshownasapotentialantimicrobialagenteffectiveagainstcertainpathogens,suchasGramnegativeandGrampositivebacteriaandthefungusCandidaalbicans.

Source:RecombinanthumanCCL28,producedinE.coli,correspondstoaa23-127(accessionno.Q9NRJ3).

ProteinSequence:ILPIASSCCTEVSHHISRRLLERVNMCRIQRADGDCDLAAVILHVKRRRICVSPHNHTVKQWMKVQAAKKNGKGNVCHRKKHHGKRNSNRAHQGKHETYGHKTPY

MolecularMass:12.073kDabyMassSpec.

Purity:>97%

Activity:EC50=38nMdeterminedbyMigrationAssayinL1.2cellsexpressingCCR10.

EndotoxinLevel:<0.01EUper1ugofproteinbyLALmethod.

Form:Lyophilized.

CarrierProtein:None.

Reconstitution:Recommendedat100ug/mlinsteriledistilledwater.

StABIlityandStorage:12monthsfromdateofreceipt,-20oCto-70oC,assupplied.

1month,2oCto8oC,understerileconditionsafterreconstitution.

3months,-20oCto-70oC,understerileconditionsafterreconstitution.

Forinvitroinvestigationaluseonly.Notforuseindiagnosticortherapeuticprocedures.

美国QED Bioscience 公司（www.qedbio.com）是专业的抗体公司，有20年的历史，是世界著名的抗体生产商。QED生物科技为科研客户提供优质的单克隆和多克隆抗体产品。 是一家提供全面服务的并提供额外服务的公司，能提供超过1500的单克隆和多克隆抗体的用于多领域的研究。