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主营:单克隆和多克隆抗体
℡ 4000-520-616
℡ 4000-520-616
QED Bioscience/Recombinant CCL4 (MIP-1β), biotinylated/50191PB-50/1 Ea
产品编号:50191PB-50
市  场 价:¥41040.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$2052.00
品      牌: QED Bioscience
公      司:QED Bioscience
公司分类:
QED Bioscience/Recombinant CCL4 (MIP-1β), biotinylated/50191PB-50/1 Ea
商品介绍


RecombinantCCL4(MIP-1β),biotinylated



ORDERINGINFORMATIONORDERINGINFORMATION

CatalogNo.Size

50191PB-22ug

50191PB-1010ug

50191PB-5050ug

50191PB-100100ug


BACKGROUNDBACKGROUND

CCL4,alsoknownasMacrophageInflammatoryProtein-1beta(MIP-1β)isasmallcytokine(~9kDa)thatbelongstotheCCchemokinefamily.CCL4bindstoCCR1,CCR2isoformB,andCCR5.CCL4isoneofthemajorHIV-suppressivefactorsproducedbyCD8+T-cells;recombinantMIP-1βinducesadose-dependentinhibitionofdifferentstrainsofHIV-1,HIV-2,andsimianimmunodeficiencyvirus(SIV).TheprocessedformofMIP-1β(aa3-69)retainstheABIlitiestoinducedown-modulationofsurfaceexpressionofCCR5andtoinhibitCCR5-mediatedentryofHIV-1intoT-cells.


DESCRIPTIONDESCRIPTION

Source:RecombinanthumanCCL4isproducedinE.coli(accessionno.

P13236,aa24-92).

Modification:Biotinylated

ProteinSequence:APMGSDPPTACCFSYTARKLPRNFVVDYYETSSLCSQPAVVFQTKRSKQVCADPSESWVQEYVYDLELN

MolecularMass:10.237kDabyMassSpec.

Purity:>97%bySDS-PAGE

Activity:EC50=0.32-1.3nMdeterminedbyMigrationAssayincellsexpressingrecombinantCCR5.

EndotoxinLevel:<0.01EUper1ugofproteinbyLALmethod.

Form:Lyophilized.

CarrierProtein:None.


PREPARATIONANDSTORAGEPREPARATIONANDSTORAGE

Reconstitution:CentrifugetubepriortoresUSPending.Recommendedat100ug/mlinsteriledistilledwater.

StabilityandStorage:12monthsfromdateofreceipt,-20oCto-70oC,assupplied.

1month,-20oCto-70oC,understerileconditionsafterreconstitution.Bestifusedimmediatelyafterreconstitution.

Avoidmultiplefreeze-thawcycles.


Forinvitroinvestigationaluseonly.Notforuseindiagnosticortherapeuticprocedures.

品牌介绍

美国QED Bioscience 公司(www.qedbio.com)是专业的抗体公司,有20年的历史,是世界著名的抗体生产商。QED生物科技为科研客户提供优质的单克隆和多克隆抗体产品。 是一家提供全面服务的并提供额外服务的公司,能提供超过1500的单克隆和多克隆抗体的用于多领域的研究。

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