productdatasheet

Formulation:Sterile-filteredcolorlesssolutioncontains20mMTris-HCl,pH7.5,1mMDTT,10%glycerol,and2mMEDTA.Purifiedbyproprietarychromatographictechniques.

Alpha-1-antitrypsin(A1AT)isaserineproteaseinhibitorthatinhibitsthecatalyticdomainofelastase,plasmin,Collagenase,thrombin,leucocyticproteases,trypsin,chymotrypsin,andplasminogenactivator.DefectsintheA1ATgenecanleadtoemphysemaorliverdisease.IncreasedlevelsofserumA1ATarefoundincasesoflungandprostatecancersandasanacutephaseresponsetotissuenecrosisandinflammation.

RecombinantHumanA1ATproducedin

E.coliisasingle,non-glycosylatedpolypeptidechaincontaining393amino

acids(aa25-418)withamolecularweightof44.4kDa.

Source:EscherichiacoliPurity:Greaterthan90%asdeterminedbySDS-PAGE.Accessionnumber:P01009AminoAcidSequence:

MEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIDQNTKSPLFMGKVVNPTQK.

Althoughstableat4oCfor4weeks,productisbeststoredatorbelow-20oC.Forlong-termstorage,additionofacarrierprotein(suchas0.1%HSAorBSA)isrecommended.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

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SanDiego,CA92127

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Phone858.675.2405

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美国QED Bioscience 公司（www.qedbio.com）是专业的抗体公司，有20年的历史，是世界著名的抗体生产商。QED生物科技为科研客户提供优质的单克隆和多克隆抗体产品。 是一家提供全面服务的并提供额外服务的公司，能提供超过1500的单克隆和多克隆抗体的用于多领域的研究。