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ThisantibodyreactswiththeheavychainofhumanFactorXII(mw~50,000)withKDof9.8nMandpartiallyblocksFactorXIIactivity.Thespecificepitopeforthisantibodyislocatedwithina20aminoacidsequenceof2.5kDinthesurfacebindingareaofFactorXII.

ThisantibodymaybeusedinELISA,Westernblot,coagulationassaysandforimmunopurificationofFactorXII.

DiluteinPBSormediumthatisidenticaltothatusedintheassaysystem.

Theseantibodiesarestableforatleastone(1)yearat-20oCto-70oC.Storeproductinappropriatealiquotstoavoidmultiplefreeze-thawcycles.

Pixleyetal.(1987)JBiolChem262:10140.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedure

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