PurifiedbyProteinGaffinitychromatography.

DicerisamemberoftheRNaseIIIfamilythatspecificallycleavesdouble-strandedRNAstogeneratemicroRNAs(miRNAs).Afterlongprimarytranscriptpri-miRNAsareprocessedtostem-loopedpre-miRNAsbyDrosha,pre-miRNAsaretransportedtothecytoplasmandfurtherprocessedbyDicertoproduce22-nucleotidematuremiRNAs.ThematuremiRNAthenbecomesapartoftheRNA-InducedSilencingComplex(RISC)andcanbindtothe3'UTRofthetargetmRNA.

Antigen:Fusionproteincorrespondingtoaa1638-1899ofmouseEndoribonucleaseDicer(accessionno.Q8R418).

Thisantibodyrecognizeshuman,mouseandratDicer.

Immunoblotting:useat1ug/ml.Predictedmolecularweightis~215kDa.

#12532onratbrainlysate.

PositiveControl:ratbrainlysate.

Thesearerecommendedconcentrations.Endusersshoulddetermineoptimalconcentrationsfortheirapplications.

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

Thisantibodyisstableforatleastone(1)yearat-20oC.Avoidrepeatedfreeze-thawcycles.

Forinvitroinvestigationaluseonly.Notintendedfordiagnosticortherapeuticapplications.

美国QED Bioscience 公司（www.qedbio.com）是专业的抗体公司，有20年的历史，是世界著名的抗体生产商。QED生物科技为科研客户提供优质的单克隆和多克隆抗体产品。 是一家提供全面服务的并提供额外服务的公司，能提供超过1500的单克隆和多克隆抗体的用于多领域的研究。