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AmicrosomalenzymeknownasProteinDisulfideIsomerase(PDI)isinvolvedintheformationofdisulfidebondsinmanyextracellularproteinsthroughitsoxidaseandisomeraseactivities.Itisalsoinvolvedinthereductionofdisulfidebondsinproteins.PDIislocatedprimarilyintheendoplasmicreticulum(ER)butmayalsobefoundinthecytosol.PDIcanresideintheERduetothehighlyconservedKDELsequenceatitscarboxyterminuswhichservesasanER-retentionsignal.
Thisantibodyrecognizeshuman,monkey,mouse,rat,hamster,bovine,ovine,porcine,canine,guineapig,andXenopusPDI.
Westernblot:Useat1:4,000dilution.Abandofapprox.58kDisdetected.
Immunocytochemistry/Immunohisto-chemistry:Useat2-5ug/ml.
Immunoprecipitation:Useat10ug/ml.
DiluteinPBSormediumthatisidenticaltothatusedintheassaysystem.
Storefrozenproductatorbelow-20oC.Foroptimalstorage,aliquottosmallerportionsandstoreat-20oCto-70oC.Avoidrepeatedfreeze/thawcycles.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
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美国QED Bioscience 公司(www.qedbio.com)是专业的抗体公司,有20年的历史,是世界著名的抗体生产商。QED生物科技为科研客户提供优质的单克隆和多克隆抗体产品。 是一家提供全面服务的并提供额外服务的公司,能提供超过1500的单克隆和多克隆抗体的用于多领域的研究。