productdatasheet

CatalogNo.:2355

Size:100ugIgGin200ulPBS,pH7.4,purifiedbyimmunoaffinitychroma-tography.

Interleukin-1(IL-1)andlipopoly-saccharide(LPS)inducecellularresponsesthroughIL-1receptornadToll-likereceptors.IL-1receptor-associatedkinases(IRAKandIRAK2)mediatetheactivationofNF-κBby

IL-1/Tollreceptors,akeystepin

inflammatoryandimmuneresponses.AnovelmemberoftheIRAKfamily,IRAK-M,isadominantnegativemutantofIRAKandinhibitsIL-1orLPSinducedNF-κBactivation.

Antigen:Peptidecorrespondingtoaa581-596ofhumanIRAK-M.

HostSpecies:Rabbit

StABIlizers:None

Preservatives:0.02%sodiumazide.

Thisantibodyrecognizeshuman,mouse,andratIRAK-M(68kD).Nocross-reactivitywithIRAKorIRAK2.

Immunoblotting:useat1:500-1:1,000dilution.

Positivecontrol:Tissuelysatefrommousespleenorratkidney.

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

Thisantibodyisstableforatleastone

(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures

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美国QED Bioscience 公司（www.qedbio.com）是专业的抗体公司，有20年的历史，是世界著名的抗体生产商。QED生物科技为科研客户提供优质的单克隆和多克隆抗体产品。 是一家提供全面服务的并提供额外服务的公司，能提供超过1500的单克隆和多克隆抗体的用于多领域的研究。