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主营:单克隆和多克隆抗体
℡ 4000-520-616
℡ 4000-520-616
QED Bioscience/IRAK (CT)/2426/1 Ea
产品编号:2426
市  场 价:¥7760.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$388.00
品      牌: QED Bioscience
公      司:QED Bioscience
公司分类:
QED Bioscience/IRAK (CT)/2426/1 Ea
商品介绍


productdatasheet


Anti-IRAK(CT)Antibody


ORDERINGINFORMATION

CatalogNo.:2426

Size:100ugIgGinPBS,pH7.4,purifiedbyimmunoaffinitychroma-tography.


BACKGROUND

NuclearfactorkappaB(NF-κB)isaubiquitoustranscriptionfactorandkeymediatorofgeneexpressionduringimmuneandinflammatoryresponses.NF-κBactivatesnumerousgenesinresponsetoextracellularstimuli,suchasIL-1,TNFα,LPS,oxidativestress,andmitogens.NF-κBisassociatedwithIκBincytoplasm.Afterstimulation,1κBisphosphorylatedanddissociatesfromNF-κB.NF-κBenterscellnucleiwhereitactivatesanarrayofgenes.Aserine/threonineproteinkinaseassociatedwithIL-1receptor(IRAK)mediatesasignalingcascadeleADIngto

NF-κBactivation.IRAKisassociatedwithIL-1receptorsubunitsIL-1RIandIL-1RacPandservesasasignalingmoleculetomediateIL-1responses.IRAKalsomediatesIL-18-inducedNF-κBactivation.

SPECIFICATIONSUMMARY

Antigen:PeptidecorrespondingtheC-terminusofhumanIRAK.

HostSpecies:Rabbit

StABIlizers:None

Preservatives:0.02%sodiumazide.


SPECIFICITY

Thisantibodyrecognizesfull-lengthhumanIRAK(80kD).


APPLICATIONS

Immunoblotting:useat1:1,000-1:2,000dilution.

Immunoprecipitation:use2-4ugantibodypersample.

Positivecontrol:WholecelllysatefromHeLacellsorTHP-1cells.


DILUTIONINSTRUCTIONS

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.


STORAGEANDSTABILITY

Thisantibodyisstableforatleastone(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.


QEDBioscience,Inc.10919TechnologyPlace,SuiteC

SanDiego,CA92127

TollFree800.929.2114

Phone858.675.2405

Fax858.592.1509

info@qedbio.com

Visitourwebsiteforadditionalproductinformationandtoorderonline.

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品牌介绍

美国QED Bioscience 公司(www.qedbio.com)是专业的抗体公司,有20年的历史,是世界著名的抗体生产商。QED生物科技为科研客户提供优质的单克隆和多克隆抗体产品。 是一家提供全面服务的并提供额外服务的公司,能提供超过1500的单克隆和多克隆抗体的用于多领域的研究。

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