CalnexinMonoclonalAntibody
Calnexinisa~90kDaintegralproteinoftheendoplasmicreticulum;itisalsoreferredtoasIP90,p88andp90.Itconsistsofa50kDaN-terminalcalcium-bindingluminaldomain,asingletransmembranehelix,and
ashortacidiccytoplasmictail.Itspositivelychargedcytosolicresiduesensureitsretentionintheendoplasmicreticulum.Calnexintogetherwithcalreticulinplayakeyroleinglycoproteinfoldingbyinteracting
withfoldingintermediatesviatheirmonoglycosylatedglycans.CalnexinhasalsobeenshowntoassociatewiththemajorhistocompatABIlitycomplexclassIheavychains,partialcomplexesoftheTcellreceptor,andBcellsurfaceimmunoglobulin.
Thisantibodyreactswithhumanand
Dictyosteliumdiscoideumcalnexin.
Immunoblotting:useat1-10ug/ml.
Immunohistochemistry:useat1-10ug/ml.
Thesearerecommendedconcentrations.Endusershoulddetermineoptimalconcentrationsfortheirapplications.
Reconstituteindistilledwater.
Thisproductisstableforatleastone(1)yearat-20oCto-70oC.Reconstitutedproductshouldbestoredinappropriatealiquotstoavoidrepeatedfreeze-thawcycles.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
美国QED Bioscience 公司(www.qedbio.com)是专业的抗体公司,有20年的历史,是世界著名的抗体生产商。QED生物科技为科研客户提供优质的单克隆和多克隆抗体产品。 是一家提供全面服务的并提供额外服务的公司,能提供超过1500的单克隆和多克隆抗体的用于多领域的研究。