productdatasheet

CatalogNo.:56465(cloneS96-55)Size:100uginPBS,pH7.4;50%glycerol,0.09%sodiumazide.PurifiedbyProteinGaffinitychromatography.

GABAisthemajorinhibitoryneuro-transmitterinthevertebratebrain.GABAreceptorsconsistoffivesubunitsthatformachlorideionchannel.Subunitfamiliesα,β,γ,andδhavebeenstudiedextensively;πandεhavebeenidentifiedrecently.

StudiesofrecombinantGABAreceptorshaveshownthatindividualsubunitsandtheirsubtypesconferdifferentsensitivitiestoGABAreceptormodulators.SubunitsubtypesaredifferentiallyexpressedthroughoutdevelopmentandindifferentCNSregions,reducingthetotalnumberofpossIBLeisoformsthatcanbeformedindifferentbrainregionsandinindividualcells.

Thisantibodyrecognizeshuman,mouse,andratBeta1GABA-Areceptor.Itdoesnotcross-reactwithBeta2orBeta3GABA-Areceptors.

Immunoblotting:useat1-10ug/ml.Abandof~55kDaisdetected.

AdultratbrainlysateImmunohistochemistryandImmunocytochemistry:useat0.1-1ug/mlImmunofluorescence:useat1-10ug/mlThesearerecommendedconcentrations.Usershoulddetermineoptimalconcentrationsfortheirapplication.

Positivecontrol:Ratbrainlysate.

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

Thisantibodyisstableforatleastone(1)yearat-20oC.Avoidrepeatedfreezingandthawing.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

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美国QED Bioscience 公司（www.qedbio.com）是专业的抗体公司，有20年的历史，是世界著名的抗体生产商。QED生物科技为科研客户提供优质的单克隆和多克隆抗体产品。 是一家提供全面服务的并提供额外服务的公司，能提供超过1500的单克隆和多克隆抗体的用于多领域的研究。