productdatasheet
CCR8isoneofthechemokinereceptorsthatarerequiredasco-receptorsforHIVinfection.ThegenesencodinghumanandmurineCCR8havebeenclonedanddesignatedTER1,CKR-L1,andChemR1.TheencodedseventransmembraneproteinwasidentifiedasthereceptorforhumanCCchemokineI-309andrenamedCCR8.Recently,CCR8wasfoundtoserveasacoreceptorfordiverseT-celltropic,dual-tropicandmacrophage-tropicHIV-1strains.CCR8mediatesCCchemokineI-309inducedmonocytechemoattractionandHIV-1envelopefusionandvirusinfection.CCR8isexpressedinspleen,thymus,andTlymphoblasticcelllines.
SPECIFICATIONSUMMARYThisantibodyrecognizeshumanCCR8(50kD).
Immunoblotting:useat1:500-1:1,000dilution.
Positivecontrol:Tissuelysatefromhumanspleen.
DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.
Thisantibodyisstableforatleastone
(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
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美国QED Bioscience 公司(www.qedbio.com)是专业的抗体公司,有20年的历史,是世界著名的抗体生产商。QED生物科技为科研客户提供优质的单克隆和多克隆抗体产品。 是一家提供全面服务的并提供额外服务的公司,能提供超过1500的单克隆和多克隆抗体的用于多领域的研究。