PurifiedbyProteinAaffinitychromatography.

TheHsp90proteinchaperoneisahighlyconservedproteincriticalfortheproperfunctioningofvariouscellularsignalingpathwaysandservestomediateappropriatefoldingandprotein-proteininteractions.Hsp90hasbeenshowntobeimportantforthegrowthofinfectiousagentssuchasPlasmodiumfalciparum,thecausativeagentofmalaria.

TreatmentwithgeldanamycineffectivelyinhibitsthegrowthofP.falciparuminculture,presumablythroughitsinteractionwithHsp90.Inaddition,arecentstudyhasshownthatPfHsp90maybemoresensitivetogeldanamycintreatmentthanitshumanhomolog.

ThisantibodyrecognizesP.falciparumHsp90anddoesnotrecognizeHsp90ofhuman,yeast,ordictyostelium..

Immunoblotting:useat1ug/ml.Abandof

~90kDaisdetected.

ImmunoblotofPfHsp90in20ugP.falciparum

lysatewith#11142at0.7ug/ml.

Immunofluorescence:useat20ug/ml.

Thesearerecommendedconcentrations.Endusersshoulddetermineoptimalconcentrationsfortheirapplications.

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

Thisantibodyisstableforatleastone(1)yearat-20oC.Avoidrepeatedfreeze-thawcycles.

Forinvitroinvestigationaluseonly.Notintendedfordiagnosticortherapeuticapplications.

美国QED Bioscience 公司（www.qedbio.com）是专业的抗体公司，有20年的历史，是世界著名的抗体生产商。QED生物科技为科研客户提供优质的单克隆和多克隆抗体产品。 是一家提供全面服务的并提供额外服务的公司，能提供超过1500的单克隆和多克隆抗体的用于多领域的研究。