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Hsp90isahighlyconservedandessentialstressproteinthatisexpressedinalleukaryoticcells.Hsp90isinvolvedinthefolding,assembly,maturation,andstABIlizationofspecificproteinsasamemberofachaperonecomplex.Itisalsohighlyexpressedinunstressedcellswhereitparticipatesincontrollingtheactivity,turnover,andtraffickingofavarietyofproteins.MostoftheHsp90-regulatedproteinsareinvolvedincellsignalingandincludethekinases,v-Src,Wee1,c-Raf,transcriptionalregulatorssuchasp53andsteroidreceptors,andthepolymerasesofhepatitisBvirusandtelomerase.

Thisantibodyrecognizeshuman,rat,andmouseHsp90β.Itdoesnotcross-reactwithHsp90α.

Immunoblotting:useat1:20,000-1:40,000(ECL).Abandof~90kDaisdetected.

Positivecontrol:HeLacelllysate

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

Thisantibodyisstableforatleastone

(1)yearat-20oC.Avoidrepeatedfreezingandthawing.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

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美国QED Bioscience 公司（www.qedbio.com）是专业的抗体公司，有20年的历史，是世界著名的抗体生产商。QED生物科技为科研客户提供优质的单克隆和多克隆抗体产品。 是一家提供全面服务的并提供额外服务的公司，能提供超过1500的单克隆和多克隆抗体的用于多领域的研究。