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主营:单克隆和多克隆抗体
℡ 4000-520-616
℡ 4000-520-616
QED Bioscience/Hsp90/11113/1 Ea
产品编号:11113
市  场 价:¥5800.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$290.00
品      牌: QED Bioscience
公      司:QED Bioscience
公司分类:
QED Bioscience/Hsp90/11113/1 Ea
商品介绍


productdatasheet


Anti-Hsp90MonoclonalAntibodyORDERINGINFORMATIONCatalogNo.:11113(clone4F3.E8)Size:100ugProteinG-purifiedantibodyinPBS,pH7.4.


BACKGROUND

Hsp90isanabundantlyandubiquitouslyexpressedheatshockproteinfoundinalleukaryoticcells.Itexistsintwoprincipalforms,αandβ,whichshare85%sequencehomology.Bothformsareexpressedinthecytosol.Hsp90αexistsprimarilyasahomodimerwhileHsp90βexistsmainlyasamonomer.

Hsp90playsaroleinfolding,assembly,maturation,andstABIlizationofspecificproteinsasakeycomponentofachaperonecomplex.MostoftheHsp90-regulatedproteinsthathavebeenidentifiedareinvolvedincellsignaling;kinases,v-Src,Wee1,c-Raf,andp53aresomeexamples.WhenboundtoATP,Hsp90interactswithco-chaperonesCdc37,p23,andvariousimmunophilin-likeproteinstoformcomplexesthatstabilizeandprotecttargetproteinsfromproteasomaldegradation.


SPECIFICATIONSUMMARYHostSpecies:Mouse

Antigen:RecombinanthumanHsp90purifiedfromE.coli.

AntibodyClass:IgG2aPreservatives:None.SPECIFICITY

Thisantibodyrecognizeshuman,mouse,andratHsp90αandβ.Otherspecieshavenotbeentested.


APPLICATIONS

Immunoblotting:useat0.5-1ug/ml.Abandof~90kDaisdetected.

ELISA

Immunohistochemistry/Immuno-cytochemistryImunoprecipitation

Usershoulddetermineoptimalconcentrationsfortheirapplication.Positivecontrol:Heat-shockedHeLacelllysate.


DILUTIONINSTRUCTIONS

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.


STORAGEANDSTABILITY

Thisantibodyisstableforatleastone

(1)yearat-20oC.Avoidrepeatedfreezingandthawing.


Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.


10919TechnologyPlace,SuiteCSanDiego,California92127Tel.(800)929-2114/(858)675-2405Fax(858)592-1509

QEDBioscience,Inc.10919TechnologyPlace,SuiteC

SanDiego,CA92127

EmailiTnofol@lFqreedebio8.c0o0m.92w9w.w2.1q1ed4bio.com

Phone858.675.2405

Fax858.592.1509

info@qedbio.com

Visitourwebsiteforadditionalproductinformationandtoorderonline.

qedbio.com

品牌介绍

美国QED Bioscience 公司(www.qedbio.com)是专业的抗体公司,有20年的历史,是世界著名的抗体生产商。QED生物科技为科研客户提供优质的单克隆和多克隆抗体产品。 是一家提供全面服务的并提供额外服务的公司,能提供超过1500的单克隆和多克隆抗体的用于多领域的研究。

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