QED Bioscience/Tumor Necrosis Factor Receptor-1 (TNF-R1)/11062-200/1 Ea,QED Bioscience,,QED Bioscience,qedbio,QED,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：QED Bioscience/Tumor Necrosis Factor Receptor-1 (TNF-R1)/11062-200/1 Ea

产品编号：11062-200

市场价：¥9760.00

场地：美国(厂家直采)

产品分类：蛋白类>重组蛋白>细胞因子>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$488.00

品牌： QED Bioscience

公司：QED Bioscience

公司分类：

商品介绍

TumorNecrosisFactor-Receptor1(TNF-R1)PolyclonalAntibody

CatalogNumber	Quantity
11062-200	200ug

CatalogNumber	Quantity
11062-200	200ug

ORDERINGINFORMATION

SPECIFICATIONSUMMARY

Antigen:AsyntheticpeptidecorrespondingtoaportionofmouseTNF-R1.Thissequenceiscompletelyconservedinratandhuman.Accessionno.P25118.HostSpecies:Rabbit.Format:Peptideaffinitypurified.Formulation:InPBScontaining50%glyceroland0.09%sodiumazide.

BACKGROUND

Tumornecrosisfactoralpha(TNF-α),alsoknownascachetin,isamemberoftheTNFsuperfamilyofcytokinesthatisapotentlymphoidfactorwitheffecsonawiderangeoftargetcells.TNFexertsproinflamatorysignalsvabindingandinducingtrimerizationofTNF-receptor1(TNF-R1)expressedonmostnormalandtransformedcells.TNFsignalingregulateshematopoiesis,differentiation,endothelialcellactivation,apoptosis,lipidmetabolism,tumorprogression,andimmunesurveillance.

DysregulationofTNForitsreceptorsisimplicatedinnumerousdiseasesincludingcancer,osteoporosis,autoimmunedisease,diabetes,andatherosclerosis.

SPECIFICITY

Thisantibodydetectsa55kDaproteinonheatshockedHeLacelllysateSDS-PAGEimmunoblots,correspondingtothemolecularweightofTNF-R1.Thisantibodyreactswithhuman,mouse,rat,hamster,bovine,rabbit,monkey,sheep,canine,pig,Drosophila,Xenopus,andyeastTNF-R1.

APPLICATIONS

WesternBlot:1ug/ml

WesternblotanalysisofTNF-R1:Lane1MWMarkers,Lane2Heat-shockedHeLacelllysate,Lane3Jurkatcelllysate.

Immunohistochemistry(paraffin):1-10ug/ml

Humanspleentissuestainedwith#11062-200at10ug/ml.

Immunoprecipitation:12.5ug/ml

Thesearerecommendedconcentrations.Endusershoulddetermineoptimalconcentrationsfortheirapplications.

STORAGEANDSTABILITY

Storefrozenproductatorbelow-20°C.Thawedproductmaybestoredfor2-4weeksat4°C.Foroptimalstorage,aliquotandstoreat-20°C.Avoidmultiplefreeze-thawcycles.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

品牌介绍

美国QED Bioscience 公司（www.qedbio.com）是专业的抗体公司，有20年的历史，是世界著名的抗体生产商。QED生物科技为科研客户提供优质的单克隆和多克隆抗体产品。是一家提供全面服务的并提供额外服务的公司，能提供超过1500的单克隆和多克隆抗体的用于多领域的研究。