productdatasheet

CatalogNo.:35101,35102,35103

Size:100ugProteinG-purifiedantibodyinPBS,pH7.4

Antigen:PurifiedhumanplacentalIGF-1receptors.

HostSpecies:MouseAntibodyClass:IgG1StABIlizers:None

Preservatives:None.Availableonrequest.

AllthreeclonesarespecificforthehumanIGF-1receptor;35102and35103recognizetheαsubunit:

• 35101(3B7)stimulatesbindingofIGF-1and-2;stimulatesbasalandIGF-1stimulatedcellgrowth.

• 35102(1H7)inhibitsbindingofIGF-1and-2;inhibitscellgrowth.

• 35103(2C8)hasnoeffectonbindingofIGF-1or-2.

UsetheseantibodiesinresearchstudiestodelineatesignaltransductionpathwaysspecificforIGF’sandfordetectingIGF-1receptorsincrudesamples.35101maybeusedtoimmunoprecipitateIGF-1receptors.35102and35103canrecognizetheIGF-1αsubunitonimmunoblots.

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

Theseantibodiesarestableforatleastone(1)yearat-20oCto-70oC.Storeproductinappropriatealiquotstoavoidmultiplefreeze-thawcycles.

Xiongetal.(1992)ProcNatlAcadSciUSA89:5356;Lietal.(1993)Biochem

BiophysResCommun196:92.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

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美国QED Bioscience 公司（www.qedbio.com）是专业的抗体公司，有20年的历史，是世界著名的抗体生产商。QED生物科技为科研客户提供优质的单克隆和多克隆抗体产品。 是一家提供全面服务的并提供额外服务的公司，能提供超过1500的单克隆和多克隆抗体的用于多领域的研究。