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主营:单克隆和多克隆抗体
℡ 4000-520-616
℡ 4000-520-616
QED Bioscience/Epidermal Growth Factor-like Protein 7/90013/1 Ea
产品编号:90013
市  场 价:¥8600.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$430.00
品      牌: QED Bioscience
公      司:QED Bioscience
公司分类:
QED Bioscience/Epidermal Growth Factor-like Protein 7/90013/1 Ea
商品介绍


EpidermalGrowthFactor-likeProtein7MonoclonalAntibody


ORDERINGINFORMATIONCatalogNo.:90013(clone2H2)Format:100ug,ProteinA-purified,lyophilized,0.1MTris,0.1Mglycine,2%sucrose,1mg/ml.


BACKGROUND

EGF-L7(EpidermalGrowthFactorLikeProtein7)isamulti-domainproteincontainingtwoEGFlikedomainsandoneEMIdomain.Itisexpressedalmostexclusivelyinendothelialcellsandfunctionstopromotenormaldevelopmentofthevascularsystem.

EGF-L7iscapableofantagoNISTicbindingtoNotchreceptorsresultingintheinhibitionofNotchsignalinginHUVECandneuralstemcells.Inresearchmodelsinducinghypoxiaandsubsequentreoxygenation,(H/R),EGF-L7caninhibitICAM-1expressionandenhancetheinhibitionofNF-kappaBactivation.Additionally,EGF-L7isachemoattractantforendothelialcellsandbindstotheextracellularmatrix.TheoverexpressionofEGF-L7isobservedinvariouscancers,andisgenerallycorrelatedwithincreasedmetastasisandapoorprognosis.


SPECIFICATIONSUMMARYAntigen:His-taggedEGFL-7recombinantprotein.Accessionno.Q9UHF1.Hostspecies:Mouse.AntibodyClass:IgG1.Preservative:None.SPECIFICITY

ThisantibodyreactswithhumanEGFL-7protein.


APPLICATIONS

ELISA:useat1-10ug/ml.Immunoblotting:useat1-5ug/ml.Abandof~30kDaisdetected.

Immunohistochemistry:Useat2-10ug/ml.

Thesearerecommendedconcentrations.Endusershoulddetermineoptimalconcentrationsfortheirapplications.


RECONSTITUTION

Reconstituteindistilledwater.


STORAGEANDSTABILITY

Thisproductisstableforatleastone(1)yearat-20oCto-70oC.Reconstitutedproductshouldbestoredinappropriatealiquotstoavoidrepeatedfreeze-thawcycles.


Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

品牌介绍

美国QED Bioscience 公司(www.qedbio.com)是专业的抗体公司,有20年的历史,是世界著名的抗体生产商。QED生物科技为科研客户提供优质的单克隆和多克隆抗体产品。 是一家提供全面服务的并提供额外服务的公司,能提供超过1500的单克隆和多克隆抗体的用于多领域的研究。

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