CD73/5’-NucleotidaseMonoclonalAntibody
5'-nucleotidase(5'-NT),alsoknownasecto-5'-nucleotidaseorCD73(ClusterofDifferentiation73),isanenzymethatinhumansisencodedbytheNT5Egene.CD73convertsAMPtoadenosine.Thisenzymeconsistsofadimerof2identical70-kDasubunitsboundbyaglycosylphosphatidylinositollinkagetotheexternalfaceoftheplasmamembrane.AdeficiencyofNT5occursinavarietyofimmunodeficiencydiseases
Thisantibodyreactswithhuman5’-NT.
ELISA:useat1-10ug/ml.Immunoblotting:useat1-5ug/ml.Abandof~63kDaisdetected.
Immunohistochemistry:useat1-5ug/ml.
Thesearerecommendedconcentrations.Endusershoulddetermineoptimalconcentrationsfortheirapplications.
Reconstituteindistilledwater.
Thisproductisstableforatleastone(1)yearat-20oCto-70oC.Reconstitutedproductshouldbestoredinappropriatealiquotstoavoidrepeatedfreeze-thawcycles.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
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