CollagenValpha-1chainisaproteinthatinhumansisencodedbytheCOL5A1gene.Thisgeneencodesanalphachainforoneofthelowabundancefibrillarcollagens.Fibrillarcollagenmoleculesaretrimersthatcanbecomposedofoneormoretypesofalphachains.TypeVcollagenisfoundintissuescontainingtypeIcollagenandappearstoregulatetheassemblyofheterotypicfiberscomposedofbothtypeIandtypeVcollagen.ThisgeneproductiscloselyrelatedtotypeXIcollagenanditispossIBLethatthecollagenchainsoftypesVandXIconstituteasinglecollagentypewithtissue-specificchaincombinations.

MutationsinthisgeneareassociatedwithEhlers-Danlossyndrome,typesIandII.

ThisantibodyreactswithhumancollagenValpha-1chainpropeptide.TheepitoperecognizedisintheCOL2-NC2region.

Immunoblotting:useat1-5ug/ml.Immunohistochemistry:Formalin-fixed,paraffin-embeddedtissue,heat-inducedantigenretrieval.Useat1-10ug/ml.

Stainingofhumanskinwith#90010

Thesearerecommendedconcentrations.Endusershoulddetermineoptimalconcentrationsfortheirapplications.

Reconstituteindistilledwater.

Thisproductisstableforatleastone(1)yearat-20oCto-70oC.Reconstitutedproductshouldbestoredinappropriatealiquotstoavoidrepeatedfreeze-thawcycles.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

美国QED Bioscience 公司（www.qedbio.com）是专业的抗体公司，有20年的历史，是世界著名的抗体生产商。QED生物科技为科研客户提供优质的单克隆和多克隆抗体产品。 是一家提供全面服务的并提供额外服务的公司，能提供超过1500的单克隆和多克隆抗体的用于多领域的研究。