productdatasheet

CatalogNo.:34031

Size:100ugProteinG-purifiedantibodyinPBS,pH7.4.

AubiquitouslyexpressedgenedesignatedTERE1(TransitionalEpithelialResponseGene1),whichmapstochromosome1p36.11-1p36.33,hasasignificanteffectongrowthregulationofbladdercancerandmayplayanequallysignificantroleingrowthregulationofprostatecancer.TheTERE1geneislocatedbetweenthemicro-satelliteMarkersD1S2667andD1S434,achromosomelocusthathasbeenidentifiedasasiteofatumorsuppressorgeneorgenesformultipletumortypes.InducedTERE1expressionintwoprostatecarcinomacelllines,LNCaPandPC-3,decreasedproliferationupto80%withasignificantincreaseinthenumberofcellsinG1.TheTERE1transcriptispresentinmostnormalhumantissues,butisreducedorabsentinthemajorityofmuscleinvasiveTCC(TransitionalCellCarcinomaofthebladder)tumors.

Immunogen:Syntheticpeptidecorrespondingtoaminoacids32-45ofhumanTERE1.Thissequenceis85%homologouswithmouseandrat.

HostSpecies:Rabbit

AntibodyClass:PolyclonalPreservatives:None.Availableonrequest.

ThisantibodyrecognizeshumanTERE1.Otherspecieshavenotbeentested.

Immunoblotting:useat1-5ug/ml.Abandofapproximately37kDais

detected.Thesearerecommendedconcentrations.Usershoulddetermineoptimalconcentrationsfortheirapplications.

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

Thisantibodyisstableforatleastone(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

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美国QED Bioscience 公司（www.qedbio.com）是专业的抗体公司，有20年的历史，是世界著名的抗体生产商。QED生物科技为科研客户提供优质的单克隆和多克隆抗体产品。 是一家提供全面服务的并提供额外服务的公司，能提供超过1500的单克隆和多克隆抗体的用于多领域的研究。