productdatasheet

CatalogNo.:11093

Size:100ugIgGinPBS,pH7.4,purifiedbyimmunoaffinitychroma-tography.

DNAfragmentation,inducedbyDNAfragmentationfactor(DFF),isoneofthecriticalstepsinapoptosis.DFFiscomposedoftwosubunits,a40-kDacaspase-activatednuclease(DFF40)anda45-kDainhibitor(DFF45).

Recentlyanovelfamilyofcelldeath-inducingDFF45-likeeffectors(CIDEs)hasbeenidentified.HumanCIDE-3isanovelCIDE.Twotranscripts,CIDE-3andCIDE-3alpha,arepresentinHepG2andA375cells.Consistentwithitschromosomelocalizationat3p25,aregionassociatedwithhighfrequencylossofheterozygosityinmanytumors,CIDE-3mayplayanimportantroleinpreventionoftumOrigenesis.

Liang,Letal.(2003)BiochemJ370:195-203.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

Immunogen:Syntheticpeptidecorrespondingtoaminoacids10-25(LLYPKSLSRHVSVRTS)ofhuman

CIDE-3conjugatedtoKLHattheC-terminus.

HostSpecies:Rabbit

StABIlizers:NonePreservatives:None.Availableonrequest.

ThisantibodyrecognizeshumanCIDE-

3.SequencehomologytothemouseCIDE-3homolog,FSP27,is93%.

Immunoblotting:useat1:500dilution.Abandofapproximately27kDaisdetected.

Positivecontrol:HepG2celllysate.

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

Thisantibodyisstableforatleastone

(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.

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美国QED Bioscience 公司（www.qedbio.com）是专业的抗体公司，有20年的历史，是世界著名的抗体生产商。QED生物科技为科研客户提供优质的单克隆和多克隆抗体产品。 是一家提供全面服务的并提供额外服务的公司，能提供超过1500的单克隆和多克隆抗体的用于多领域的研究。